Why is Drug Withdrawal so Difficult?
Most drugs of abuse affect the nucleus accumbens, or the "pleasure center" of the brain, and directly manipulate the stimulation of dopamine activity. Over time, throughout the abuse, the neurotransmitter becomes less active, and with the discontinuation of the drug, results in abnormally low levels of dopamine, creating the withdrawal syndrome dysphoria.
Drug abuse generally begins with the search of the user for positive reinforcement, such as euphoria, or the "rush" of an "initial" high. Dysphoria is a syndrome of drug withdrawal that produces the opposite symptoms of use, such as depression, anxiety, and overwhelming craving. These symptoms are often much worse than the initial problems that led to use in the first place, and addicts often continue to use indefinitely, despite harmful consequences, in the pursuit of avoiding them.
Extended use of drugs that affect neurotransmitters could result in desensitized or reduced levels of receptors in the synapses of the brain. The negative symptoms created by this occurrence are often relentless until the brain readjusts and the activities of dopamine and other neurotransmitters are restored. Withdrawal symptoms vary with the individual and depend upon many factors, such as type of drug, length, amount, and frequency of use.
The terms "crash" and "rebound" are two words that are important when considering the concept of drug withdrawal. Part of any addiction, is the pursuit of pleasurable feelings or "high" and the object of maintaining it. As a tolerance develops the addict is forced to consume larger amounts of the drug to be able to feel the rush of initial use. It is a vicious cycle. As the amount increases in the avoidance of a "crash" or the beginning of withdrawal symptoms, the more the underlying condition worsens. "Rebound" is the return of the original symptoms, such as anxiety or depression, that prompted the abuse in the beginning. As these negative symptoms reoccur, they are often compounded and drastically multiplied, creating the compulsive nature that leads to continued use.
Drug withdrawal is often the most difficult when associated with drugs that affect the central nervous system, such as tranquilizers, nicotine, stimulants, painkillers, narcotics, and anti-depressants. Symptoms can range in severity from mild depression to life threatening situations such as delirium tremens, or chronic seizures. It is advised, that in circumstances of severe addictions, drug withdrawal should be monitored in a safe setting by a medically licensed doctor or staff. It is sometimes necessary to wean a person off of a chemical dependency slowly as opposed to "cold turkey", or all at once. In cases of chronically acute addiction, where the individual's body has grown to depend upon the drug to function, it could be extremely dangerous to abruptly cease intake of the particular substance.
Cocaine is second only to marijuana as the most prevalent drug in the United States. It is so addictive that lab studies have shown that animals will choose cocaine over food or water, accept cocaine knowing they will be punished and even press a bar over 10,000 times for a single injection of cocaine. This behavior is no different in humans addicted to cocaine, which explains why treatment is so complex.
The first step to recovery from cocaine use is detox. This is a highly unpleasant experience, simply because the body is ridding itself of the drug. Withdrawal symptoms begin during this time and may last a few days to a few weeks, depending on the person.
Cocaine withdrawal symptoms can include:
- Agitation
- Depression
- Anxiety
- Extreme fatigue
- Extreme irritability
- Apathy
- Nausea and vomiting
- Shaking
- Muscle pain
- Insomnia
As with treatment of any other drug, cocaine will involve many support meetings with other recovering addicts, individual and family counseling sessions, group therapy, fun activities to keep the person busy and distracted. With cocaine, the prolonged use of which has a drastic effect on the mind’s functioning, mentally stimulating activities are ideal.
Behavioral changes are really the most effective solution for many drug addictions, including cocaine. That means a change in friends, a change in jobs, learning alternative coping methods and even adopting different social activities. Adopting a healthier lifestyle, avoiding old activities that were previously associated with cocaine use and avoiding old stresses on the job or life in general may be the only way to leave drugs behind for good.
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